Exercise Therapy and Brain Networks: Implications for Alzheimer's Disease (2019-2020)

This Bass Connection project used imaging technology along with analysis of neuropathology and behavior to examine how genetics and environment modify risk for Alzheimer’s disease in a female mouse model. The project team compared mice with the human proteins, which develop symptoms of Alzheimer’s, with mice with the human proteins, which are not at risk. Along with the laboratory-based and data-driven empirical work, the team explored how inherent characteristics and acquired life experience contribute to health and disease. There was also an imaging and visualization component focused on network analysis, based on integrating MRI with behavioral data.

Timing

Fall 2019 – Summer 2020

See related teams, Exercise Therapy and Brain Networks: Implications for Alzheimer’s Disease (2020-2021) and Exercise Therapy and Brain Networks: Implications for Alzheimer’s Disease and Aging (2018-2019).

 

Image: Jogging on a bright November morning, by Ed Yourdon, licensed under CC BY-NC-SA 2.0

Jogging on a bright November morning, by Ed Yourdon.

Team Leaders

  • Alexandra Badea, School of Medicine-Radiology
  • Christina L. Williams, Arts & Sciences-Psychology and Neuroscience

/graduate Team Members

  • Xinlin Chen, Electrical/Computer Engg-PHD
  • Janai Williams, Psychology-PHD

/undergraduate Team Members

  • Sachin Jaishankar
  • Abinaya Lakshmanan, Biomedical Engineering (BSE), Computer Science (AB2)

/yfaculty/staff Team Members

  • Carol Colton, School of Medicine-Neurology
  • Ara Wilson, Arts & Sciences-Gender, Sexuality, and Feminist Studies