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Alcohol Use Behavioral Phenotyping Test for Global Populations (2025-2026)

This project team investigated whether the Alcohol Use Behavioral Phenotyping Test (AUBPT), a web-based assessment that uses behavioral tasks rather than self-reported alcohol use, can provide a culturally adaptable and scientifically robust way to assess risk for Alcohol Use Disorder (AUD). The research addressed a growing global need for screening tools that can be effectively translated and implemented across diverse languages, cultures and health care settings.

In 2025-2026, the team advanced data collection, validation and analysis efforts across study sites in the United States, Brazil and Tanzania. Researchers collected behavioral and survey data, conducted focus groups and interviews to refine translations and cultural adaptations, and evaluated the feasibility of implementing AUBPT in clinical settings. Preliminary analyses found meaningful associations between AUBPT behavioral measures and established indicators of AUD severity, supporting the tool's potential validity.

The team's work helped move AUBPT from a fully developed digital platform toward an empirically validated global health tool. By identifying implementation challenges, refining culturally appropriate assessment methods and generating early evidence of effectiveness, the project strengthened the foundation for future large-scale studies and broader use of AUBPT in diverse communities worldwide.

Timing

Fall 2025 – Spring 2026

Team Outputs

Poster presentation (MaryAnn Black Distinguished Health Equity Symposium; Durham, N.C.; February 2026)

Screening for Alcohol Use Disorder through Games: Alcohol Use Behavioral Phenotyping Test (AUBPT) (Poster presentation at the Fortin Foundation Bass Connections Showcase, April 15, 2026)

Completed data collections for the pilot study in Brazil 

Completed data collection for the pilot study in Tanzania 

Completed the quantitative data collection for the pilot study in Durham, N.C.

NHI R21 grant submissions

See related teams, Alcohol Use Behavioral Phenotyping Test for Global Populations (2024-2025) and Alcohol Use Behavioral Phenotyping Test for Global Populations (2026-2027).

 

Team Leaders

  • Mia Buono, Franklin Humanities Institute
  • Paige O'Leary, School of Medicine: Surgery: Emergency Medicine
  • Catherine Staton, Duke Global Health Institute, School of Medicine, School of Medicine: Surgery
  • Joao Vissoci, School of Medicine: Surgery: Emergency Medicine
  • Siddhesh Zadey, School of Medicine: Surgery

Graduate Team Members

  • Jennifer Jensen, Doctor of Nursing Practice
  • Anvita Kulshrestha, Genetics & Genomics Prgm - PHD

Undergraduate Team Members

  • Meghna Koya, Biomedical Engineering (BSE)
  • Rachel Kurapati, Computer Science (BS)
  • Rafael Mautner, Mathematics (BS)
  • Hart Rodriguez Young, Biology (BS)

Community Team Members

  • Editruda Gamassa, Kilimajaro Christian Medical Center
  • Florence Jaguga, Moi Teaching and Referral Hospital
  • Suyog Jaiswal, AIIMS-Nagpur
  • Leonardo Oliveira, University of Sao Paulo, Maringa Campus, Brazil
  • Francis Sakita, Kilimanjaro Christian Medical Center

Team Contributors

  • Eric Green, Duke Global Health Institute
  • Eve Puffer, Arts & Sciences: Psychology and Neuroscience, Duke Global Health Institute